What is in Kligman’s formula?
Kligman’s formula has hydroquinone (4%-5%), tretinoin (0.025% to 0.1%), and hydrocortisone 1%
The hydroquinone is a tyrosinase inhibitor that stops production of melanin (skin pigment). Tretinoin helps skin turnover and ‘flushes’ pigmentation out. Hydrocortisone stops inflammation caused by tretinoin/hydroquinone as inflammation can cause pigmentation.
It is the gold standard in skin lightening.